

If your doctor has chosen to transition you from OxyContin® to Xtampza® ER, you can rest assured that Xtampza ER and OxyContin both contain the same pain reliever, oxycodone.
Helping you transition from OxyContin to Xtampza ER
(oxycodone HCl)
(oxycodone)
reliever in both

Only 1 option

Must swallow
tablet whole
More options available

Swallow the
capsule whole

Sprinkle on
soft foods

Sprinkle
into a cup
- You can open the capsule and sprinkle the medicine if you dislike, or have trouble, swallowing capsules
- Xtampza ER can also be delivered through a feeding tube
- Xtampza ER MUST be taken with food
Only 1 option

tablet whole
More options available

Swallow the
capsule whole

Sprinkle on
soft foods

Sprinkle
into a cup
- You can open the capsule and sprinkle the medicine if you dislike, or have trouble, swallowing capsules
- Xtampza ER can also be delivered through a feeding tube
- Xtampza ER MUST be taken with food
















Equal amount of oxycodone dose to dose
Capsules and tablets are not actual size.
The number of oxycodone milligrams in OxyContin is the same as the corresponding dose of Xtampza ER. OxyContin appears to have more milligrams because oxycodone HCl weighs more than oxycodone.
- No downloadable co-pay card
More favorable coverage
- Lower average co-pays
- Downloadable co-pay card
In a clinical study, Xtampza ER provided more pain relief than placebo.
Answers to common questions about transitioning to Xtampza ER
The pain reliever in your medication will stay the same. Both OxyContin and Xtampza ER are forms of extended-release oxycodone.
Like OxyContin, Xtampza ER is taken twice a day, every 12 hours. Xtampza ER MUST be taken with food. That’s because food helps your body absorb the medicine to relieve your pain. Take it with approximately the same amount of food each time.
Xtampza ER is the latest formulation of extended-release oxycodone available, and therefore offers some potential benefits.
- Xtampza ER can be taken several ways if you have difficulty or dislike swallowing pills, while still providing your medication at the rate and consistent level intended. You can take Xtampza ER by swallowing the capsule whole, sprinkling it on soft foods or into a cup. Misusing OxyContin even to make it easier to swallow by, crushing, cutting, chewing or dissolving it, can result in a dangerous spike of medication levels in your blood.1 Xtampza ER does not carry this same risk.2 The use of oxycodone, including Xtampza ER, exposes patients and others to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death.
- Xtampza ER resists manipulation in ways OxyContin does not, and does not carry the same warnings against its dangers.1,2 Opioids can be stolen, misused, and abused leading to risks for your family, friends, and surrounding communities. There is no way to know how a drug will affect the health of someone who uses another person’s medication, especially if they manipulate it for any reason. It is important to protect yourself and your prescription.
- Xtampza ER also has a lower co-pay for most people. There’s also an Xtampza ER co-pay card for eligible patients at XtampzaER.com/savings, to help offset costs.*
Always ask your healthcare professional if you have more questions about the transition.
1. OxyContin [package insert]. Stamford, CT: Purdue Pharma LP; 2021. 2. Xtampza ER [package insert]. Stoughton, MA: Collegium Pharmaceutical, Inc.; 2021.
*Offer valid for commercially insured patients only. Maximum savings limit applies; patient out-of-pocket expense may vary.